The University of Southern Denmark was established in 1966.
Several major industries are located in the city including the Albani Brewery and GASA, Denmark's major dealer in vegetables, fruits and flowers.The city is home to Odense Palace, erected by King Frederik IV who died there in 1730, the Odense Theatre, the Odense Symphony Orchestra, and the Hans Christian Andersen Museum, situated in the house that was the birthplace of Hans Christian Andersen. Odense is served by Hans Christian Andersen Airport and Odense station, which lies on the line between Copenhagen and the Jutland peninsula.It was here the English monk Ælnoth wrote Denmark's first literary work, Vita et Passio S. In the Middle Ages, a number of churches and monasteries were built in the town. Knuds Kirke), now the cathedral, dates from the end of the 13th century and was closely connected to the Benedictine Order.The town's other old churches are St Mary's (Vor Frue Kirke) and St John's (Skt. Greyfriars Monastery (Gråbrødre Kloster) was founded by the Franciscans in 1279.In 1720, Frederick IV ordered the rebuilding of Odense Palace, partly on the foundations of the 13th century St.
Hans’s Monastery, and the construction of St Hans’s Church by the Knights Hospitallers.
Although the city was burned in 1249 following a royal rivalry, it quickly recovered and flourished as a centre of commerce in the Middle Ages.
After a period of decline, large-scale plans for development were made during the 18th century, which led to the rebuilding of Odense Palace and the building of a canal to the Port of Odense, facilitating trade.
An 8 kilometre (5.0 mi) long, 7.5 metre (25 ft) deep canal from Odense Harbour to Odense Fjord was built between 17 to facilitate the growth of Odense as a port city, radically increasing its level of trade and population.
From the 1840s, the city enjoyed a period of rapid expansion beyond its traditional boundaries, becoming Denmark's second largest city.
Odense has close associations with Hans Christian Andersen who is remembered above all for his fairy tales.